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The simple rule for start-up survival is to focus on the 80/20 rule-the 20% of tasks that generate 80% of the benefit.My first year at business school, I thought my professors were trying to kill me. Each night, I had more reading and homework than could possibly get done in one evening even if I stayed up all night. I quickly realized that one of the key lessons of survival was prioritization--figuring out what portion of the work was most important and what just was not going to get done.I remember one night, working on a term paper with a group of students. We had worked hard on the paper and we all thought it was in good shape. We had other work to complete that night and were not anxious to pull an all-nighter so we were ready to move on